The duo stepped out of the SpaceX Dragon capsule at 11:52 BST on Thursday, embarking on the historic walk 435 miles (700km) above Earth.
Isaacman, who funded the Polaris Dawn mission, was the first to exit the capsule, testing his specially designed suit while floating in the vacuum of space. “Back at home we all have a lot of work to do, but from here Earth sure looks like a perfect world,” Isaacman commented, marvelling at the view.