Tuchel briefly experimented with both Matthijs de Ligt and Noussair Mazraoui as defensive midfielders towards the end of the draw with Leverkusen following Kimmich’s second-half withdrawal, but the German’s potential absence on Wednesday will likely see Konrad Laimer start in centre-midfield alongside Goretzka.
Former Tottenham Hotspur talisman Kane has scored four goals in as many Bundesliga games so far this season, and the England captain is set to be joined in attack by Serge Gnabry and former Manchester City winger Leroy Sane, while Jamal Musiala, who has recovered from injury, will battle with Thomas Muller for a start in the number 10 role.